Internet of things-based pulmonary rehabilitation for moderate-to-severe chronic obstructive pulmonary disease: a prospective non-randomized controlled intervention study protocol - Report - MDSpire

Internet of things-based pulmonary rehabilitation for moderate-to-severe chronic obstructive pulmonary disease: a prospective non-randomized controlled intervention study protocol

  • By

  • Nianci Guo

  • Shukun Chai

  • Runlu Wang

  • Xiaoqian Gu

  • Jie Chen

  • Huikun Zhao

  • Kaili Qie

  • Wentao Ni

  • Jinying Shi

  • June 9, 2026

  • 0 min

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Clinical Report: Utilizing IoT Technology for Pulmonary Rehabilitation in COPD

Overview

This study protocol outlines a prospective non-randomized controlled intervention aimed at evaluating the effectiveness of Internet of Things (IoT) technology in enhancing pulmonary rehabilitation (PR) for patients with moderate-to-severe chronic obstructive pulmonary disease (COPD). The intervention seeks to improve adherence and clinical outcomes by integrating IoT devices for home-based rehabilitation.

Background

Chronic obstructive pulmonary disease (COPD) is a significant global health issue characterized by persistent respiratory symptoms and airflow limitation, leading to increased morbidity and healthcare costs. Pulmonary rehabilitation is a critical non-pharmacological intervention that can improve patient outcomes, yet adherence remains a challenge, particularly in home settings. The integration of IoT technology may address these challenges by providing real-time monitoring and personalized support.

Data Highlights

This study will enroll 588 patients with moderate-to-severe stable COPD, comparing conventional PR with IoT-assisted PR over a 12-month period.

Key Findings

  • The primary outcome is the rate of moderate-to-severe acute exacerbations of COPD (AECOPD) over 12 months.
  • Secondary outcomes include pulmonary function, exercise capacity, health-related quality of life (HRQoL), and adherence rates.
  • Participants in the IoT-assisted group will utilize devices and a smartphone app for daily training sessions.
  • Follow-up assessments will occur at weeks 4, 12, 26, and 52.
  • This study aims to evaluate the feasibility and safety of IoT in a real-world setting for COPD management.

Clinical Implications

The findings from this study could inform the development of technology-enabled continuous care models for COPD, potentially enhancing patient engagement and adherence to rehabilitation programs. This may facilitate a shift towards more patient-centric care approaches in chronic respiratory disease management.

Conclusion

The integration of IoT technology in pulmonary rehabilitation for COPD patients may significantly improve adherence and clinical outcomes, addressing longstanding challenges in traditional rehabilitation models.

Related Resources & Content

  1. DIGITAL HEALTH, SAGE Journals, 2026 -- Efficacy of IoT-based perioperative respiratory rehabilitation for lung resection: Protocol of a randomized controlled trial
  2. JMIR Medical Informatics, 2026 -- AI and Internet of Things for Chronic Obstructive Pulmonary Disease Remote Monitoring: Systematic Review of Exacerbation Prediction and Key Physiological Variables
  3. Frontiers in Medicine, 2026 -- Comparative efficacy of single exercise interventions on pulmonary function and quality of life in patients with chronic obstructive pulmonary disease: a systematic review and network meta-analysis
  4. Global Initiative for Chronic Obstructive Lung Disease, 2026 -- GOLD 2026 global strategy for the prevention, diagnosis, and management of COPD
  5. Frontiers in Medicine — Mobile health for chronic obstructive pulmonary disease: a bibliometric analysis based on integrated databases (2000–2025)
  6. Comparing Pulmonary Telerehabilitation and Center-Based Pulmonary Rehabilitation for Effectiveness and Adherence in Chronic Obstructive Pulmonary Disease
  7. Global Initiative for
  8. A randomised controlled study of the efficacy of Internet of Things-based telerespiratory rehabilitation for chronic respiratory diseases | BioMedical Engineering OnLine | Springer Nature Link

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