Evaluating the Long-Term Effects of COVID-19 on Various Sensory Functions - Report - MDSpire

Evaluating the Long-Term Effects of COVID-19 on Various Sensory Functions

  • By

  • Ahmad Odeh

  • Veronica L. Formanek

  • Christina Smith

  • Nidhi Jha

  • Junichi Tajino

  • Jessica H. Lewis

  • Lauren Gastineau

  • Shivani Patel

  • Songzhu Zhao

  • Lai Wei

  • Aaron C. Moberly

  • Daniel M. Merfeld

  • Christopher T. Simons

  • Megan J. Kobel

  • Kai Zhao

  • February 27, 2026

  • 0 min

Share

Clinical Report: Evaluating the Long-Term Effects of COVID-19 on Sensory Functions

Overview

This study investigates the long-term impacts of COVID-19 on sensory functions, including smell, taste, hearing, and balance. Findings indicate that a significant proportion of patients experience persistent sensory dysfunctions well beyond the acute phase of infection.

Background

The COVID-19 pandemic has led to widespread health complications, including neurological symptoms and sensory dysfunction. Smell and taste impairments are particularly notable, with emerging evidence suggesting that these issues may persist long after the initial infection. Understanding the long-term effects on sensory functions is crucial for developing effective management strategies for affected patients.

Data Highlights

No numerical data available in the source material.

Key Findings

  • 73-76% of COVID-19 patients report long-term symptoms 60-180 days post-diagnosis.
  • Common persistent symptoms include fatigue, muscle weakness, and neurological disorders.
  • Up to 15-20% of patients experience changes in hearing, tinnitus, or dizziness.
  • Loss of taste and chemesthesis may occur independently of olfactory dysfunction.
  • Neurological inflammation may contribute to sensory dysfunctions observed in COVID-19 patients.

Clinical Implications

Healthcare providers should be aware of the potential for long-term sensory dysfunction in COVID-19 patients. Comprehensive sensory assessments may be necessary for those reporting ongoing symptoms, and tailored management strategies should be developed to address these issues.

Conclusion

The study highlights the significant and lasting impact of COVID-19 on sensory functions, emphasizing the need for continued research and clinical attention to these complications in post-COVID care.

References

  1. Retinal Physician, October 2023 -- Effects of COVID-19 Infection and Vaccination in the Retina
  2. Open Forum Infectious Diseases, 2023 -- Health-Related Quality of Life Outcomes Two Years Post Mild to Moderate SARS-CoV-2 Infection
  3. Open Forum Infectious Diseases, 2023 -- Impact of SARS-CoV-2 on Health-Related Quality of Life One Year Post-Infection
  4. Long COVID Clinical Guidance | Long COVID | CDC
  5. Clinical management of COVID-19: living guideline, June 2025
  6. Open Forum Infectious Diseases — Cognitive Abilities One Year Post-COVID-19 Infection
  7. COVID-19 Linked to Lasting and Underrecognized Smell Impairment | JAMA
  8. Objective assessment of long-term impact of COVID-19 on multiple sensory functions
  9. Long COVID Clinical Guidance | Long COVID | CDC
  10. Clinical management of COVID-19: living guideline, June 2025
  11. COVID-19 rapid guideline:
  12. graphical abstract 24-081 infanger serrano copy
  13. APOLLO trial: a proof-of-concept study for vitamin A nasal drops in COVID-19-related postinfectious olfactory dysfunction | Chemical Senses | Oxford Academic
  14. Multidimensional benefits of olfactory training for chronic COVID-19-related olfactory dysfunction: a systematic review and meta-analysis - PubMed
  15. Comparative efficacy and safety of pharmacological interventions for the treatment of long COVID in adults: a systematic review and network meta-analysis
  16. https://www.thieme-connect.com/products/ejournals/pdf/10.1055/s-0045-1802968.pdf
  17. Long-term neurological and cognitive impact of COVID-19: a systematic review and meta-analysis in over 4 million patients - PubMed

Original Source(s)

Related Content