Implantation of cardiac resynchronization therapy defibrillator with left bundle branch pacing in a patient with mirror-image dextrocardia: a case report - Report - MDSpire

Implantation of cardiac resynchronization therapy defibrillator with left bundle branch pacing in a patient with mirror-image dextrocardia: a case report

  • By

  • Hongwei Yi

  • Jia Li

  • Hongwei Han

  • Yue Bao

  • June 9, 2026

  • 0 min

Share

Clinical Report: Cardiac Resynchronization Therapy Defibrillator Implantation with Left Bundle Branch Pacing in a Patient with Mirror-Image Dextrocardia

Overview

This report details a case of cardiac resynchronization therapy defibrillator implantation using left bundle branch pacing in a 73-year-old male with mirror-image dextrocardia and advanced heart failure.

Background

Mirror-image dextrocardia is a rare congenital condition with an incidence of approximately 0.01%. The complete reversal of cardiac anatomy complicates standard cardiovascular interventions, particularly in patients requiring cardiac pacing. Cardiac resynchronization therapy (CRT) is recommended for heart failure patients with complete left bundle branch block, but its application in mirror-image dextrocardia has been minimally explored.

Data Highlights

No numerical data or trial data provided in the source material.

Key Findings

  • Successful implantation of an LBBP-based CRT-D in a patient with mirror-image dextrocardia.
  • Preoperative mirror-image adaptation of ECG and DSA systems was crucial for the procedure.
  • Advanced heart failure and CLBBB were present in the patient.
  • Accurate capture of the left bundle branch was achieved intraoperatively.

Clinical Implications

This case underscores the importance of tailored approaches in CRT for patients with unique anatomical challenges. The successful use of LBBP in this context may inform future practices for similar cases.

Conclusion

The implantation of an LBBP-based CRT-D in a patient with mirror-image dextrocardia demonstrates the feasibility of this approach despite significant anatomical challenges. This case contributes valuable knowledge to the field of cardiac pacing in complex congenital conditions.

Related Resources & Content

  1. Author(s)/Org, Source, Year -- Title
  2. Frontiers in Cardiovascular Medicine — Case Report: Leadless pacemaker implantation in patient with Senning procedure for dextro-transposition of the great arteries
  3. Pediatric Cardiology — Pediatric Conduction System Pacing and Congenital Heart Disease: Insights from a Series of 24 Cases at a Single Institution
  4. Pediatric Cardiology — Dual Chamber Aveir Retrievable Leadless Pacemaker Implant in a Patient with a Senning Baffle and Subcutaneous ICD
  5. npj Digital Medicine — Accelerated Assessment of Left Ventricular Cardiac Activation Using Geometric Deep Learning: Advancing Planning for Cardiac Resynchronization Therapy
  6. Dextrocardia: Causes, Treatment & Outlook
  7. https://academic.oup.com/eurheartj/article/46/29/2844/8160336
  8. ACC/AHA/ASE/HFSA/HRS/SCAI/SCCT/SCMR 2025 Appropriate Use Criteria for Implantable Cardioverter-Defibrillators, Cardiac Resynchronization Therapy, and Pacing - American College of Cardiology
  9. Left bundle branch area vs biventricular pacing for cardiac resynchronization therapy: the LEFT-BUNDLE-CRT trial | European Heart Journal | Oxford Academic
  10. Left bundle branch area pacing compared with biventricular pacing for cardiac resynchronization therapy in patients with left ventricular ejection fraction ≤50%: Results from the International Collaborative LBBAP Study (I-CLAS) - ScienceDirect
  11. Frontiers | Left bundle branch area pacing vs. biventricular pacing significantly improves clinical outcomes and cardiac remodeling in cardiac resynchronization therapy: a systematic review and meta-analysis
  12. CARDIAC RESYNCHRONIZATION THERAPY IN DEXTROCARDIA WITH SITUS INVERSUS TOTALIS: STRATEGIES AND OUTCOMES INVOLVING CORONARY SINUS CANNULATION | JACC
  13. Successful Cardiac Resynchronization Therapy With Defibrillator Implantation in a Patient With Isolated Dextrocardia and Situs Inversus Totalis: Role of High‐Resolution Three‐Dimensional Computed Tomography in Procedural Planning - PMC
  14. Left bundle branch area pacing for pacing-induced cardiomyopathy in a patient with dextrocardia after ventricular septal defect closure - PubMed
  15. 26-CCC-18892-ACC LEFT BUNDLE AREA PACING AND CRT-D IN A PATIENT WITH DEXTROCARDIA, SITUS INVERSUS, AND MUSCULAR DYSTROPHY: A CASE OF COMPLEX ARRHYTHMIA MANAGEMENT | JACC
  16. Frontiers | Implantation of Cardiac Resynchronization Therapy Defibrillator with Left Bundle Branch Pacing in a Patient with Mirror-Image Dextrocardia: A Case Report

Original Source(s)

Related Content