Efficacy and safety of transcatheter left atrial appendage closure guided by transoesophageal echocardiography using standard and micro TEE probes: a single-center retrospective study - Report - MDSpire

Efficacy and safety of transcatheter left atrial appendage closure guided by transoesophageal echocardiography using standard and micro TEE probes: a single-center retrospective study

  • By

  • Alessandro Barbarossa

  • Francesca Coraducci

  • Elisa Nicolini

  • Laura Cipolletta

  • Alessandro Maolo

  • Michela Casella

  • Fabio Vagnarelli

  • Federico Guerra

  • Marco Marini

  • Antonio Dello Russo

  • Tommaso Piva

  • June 9, 2026

  • 0 min

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Clinical Report: Efficacy and Safety of Micro-TEE in T-LAAC Procedures

Overview

Expand on the implications of shorter procedural times and similar complication rates.

Background

Transcatheter left atrial appendage closure (T-LAAC) is a critical intervention for patients with atrial fibrillation (AF) who cannot use long-term anticoagulation. Effective imaging during the procedure is essential for success and safety. The introduction of micro-TEE offers a potential alternative to standard TEE, allowing for conscious sedation and possibly reducing procedural complications and time.

Data Highlights

ParameterStandard TEEMicro-TEE
Procedural Time (min)175153
Orotracheal Intubation RateHigherLower
Complication RateNo significant differenceNo significant difference

Key Findings

  • Micro-TEE guidance resulted in a significantly shorter procedural time (153 vs. 175 min, p = 0.040).
  • There was no significant difference in procedural success rates between micro-TEE and standard TEE.
  • Complication rates, including pericardial effusion and device-related thrombosis, were similar for both imaging modalities.
  • Micro-TEE was associated with a lower rate of orotracheal intubation.
  • No increase in fluoroscopy time, radiation exposure, or contrast use was observed with micro-TEE.

Clinical Implications

The findings suggest that micro-TEE can be a viable alternative to standard TEE for T-LAAC, potentially reducing the need for general anesthesia and associated complications. This may enhance patient comfort and streamline procedural workflows in clinical practice.

Conclusion

Micro-TEE demonstrates comparable efficacy and safety to standard TEE in T-LAAC procedures while offering advantages in procedural efficiency. Its adoption may improve patient outcomes and procedural experiences.

Related Resources & Content

  1. Zhang Z-Y et al., Frontiers in Cardiovascular Medicine, 2023 -- Correction: A comparable efficacy and safety between intracardiac echocardiography and transesophageal echocardiography for percutaneous left atrial appendage occlusion
  2. Frontiers in Cardiovascular Medicine, 2023 -- Comparative Study on the Efficacy and Safety of Different Left Atrial Appendage Occluders in One-Stop Atrial Fibrillation Procedures
  3. Clinical Research in Cardiology, 2025 -- Evaluation of Treatment Approaches for Atrial Fibrillation Patients with Left Atrial Appendage Thrombus Despite Optimal NOAC Management
  4. 2025 SCAI/HRS Clinical Practice Guidelines on Transcatheter Left Atrial Appendage Occlusion - PMC
  5. 2024 ESC Guidelines for the management of atrial fibrillation, European Heart Journal
  6. Clinical Research in Cardiology — Impact of Atrial Myopathy on Safety Outcomes in Left Atrial Appendage Closure for Mitral Valve Disease
  7. Percutaneous Left Atrial Appendage Closure (LAAC) | CMS
  8. Left Atrial Appendage Closure after Ablation for Atrial Fibrillation - PubMed
  9. 2025 SCAI/HRS Clinical Practice Guidelines on Transcatheter Left Atrial Appendage Occlusion - PMC
  10. 2024 ESC Guidelines for the management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS) | European Heart Journal | Oxford Academic
  11. 2024 ESC Guidelines for Management of Atrial Fibrillation: Key Points - American College of Cardiology
  12. Left Atrial Appendage CLOSURE in Patients with Atrial Fibrillation at High Risk of Stroke and Bleeding Compared to Medical Therapy - American College of Cardiology
  13. Left Atrial Appendage Closure Noninferior to Blood Thinners for Lowering Stroke Risk, Death in Some Patients with AFib - American College of Cardiology
  14. Intracardiac or transesophageal echocardiography for left atrial appendage occlusion: an updated systematic review and meta-analysis | The International Journal of Cardiovascular Imaging | Springer Nature Link
  15. Safety and Feasibility of 3D Intracardiac Echocardiography in Guiding Left Atrial Appendage Occlusion With WATCHMAN FLX - PubMed
  16. Moderate conscious sedation for transesophageal echocardiography guidance of percutaneous left atrial appendage closure: The MID-DEX protocol - PubMed
  17. Clinical Outcomes of the First 200 Cases of Single-Operator TEE-Guided Left Atrial Appendage Occlusion (SOLOCLOSE) - ScienceDirect
  18. Feasibility and Safety of Transnasal Transesophageal Echocardiography Guiding Left Atrial Appendage Closure Without General Anesthesia | JACC: Cardiovascular Imaging

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