Sudden Sensorineural Olfactory Loss (SSNOL): A Structured Narrative Review and Proposal for a Standardised Terminological Framework - Report - MDSpire

Sudden Sensorineural Olfactory Loss (SSNOL): A Structured Narrative Review and Proposal for a Standardised Terminological Framework

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  • AL-BAR, MOHAMMAD

  • April 28, 2026

  • 0 min

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Clinical Report: Acute Sensorineural Olfactory Dysfunction Overview

Overview

This report reviews the condition of sudden sensorineural olfactory loss (SSNOL), highlighting the inadequacy of current terminology and diagnostic tools. It proposes a unified term, SSNOL, to enhance research and clinical management.

Background

Acute sensorineural olfactory dysfunction is a significant clinical issue that can lead to debilitating consequences for patients. The lack of standardized terminology and diagnostic criteria has resulted in delays in diagnosis and treatment. This review aims to address these gaps and improve the understanding and management of this condition.

Data Highlights

No numerical data presented in the article.

Key Findings

  • Sudden sensorineural olfactory loss (SSNOL) is proposed as a unified term for acute olfactory dysfunction.
  • Current diagnostic tools for olfactory loss are inadequate and blunt.
  • Olfactory training is the only intervention with consistent evidence supporting its effectiveness.
  • Post-viral olfactory loss has gained attention due to its prevalence following the COVID-19 pandemic.
  • Two aetiological categories, SSNOL-Viral and SSNOL-Idiopathic, are suggested for future research guidance.

Clinical Implications

Clinicians should adopt the term Sudden Sensorineural Olfactory Loss (SSNOL) to facilitate better communication and research. Emphasis on olfactory training as a first-line treatment can improve patient outcomes in cases of post-viral olfactory dysfunction.

Conclusion

The introduction of a standardized term for acute sensorineural olfactory loss is crucial for advancing research and clinical practice. Improved terminology and focused research efforts are necessary to enhance patient care in this area.

Related Resources & Content

  1. Frontiers in Medicine, 2026 -- Neurobiological mechanisms of olfactory dysfunction: a ten-year bibliometric and visualization analysis
  2. Frontiers in Neurology, 2026 -- Targeting ferroptosis in sensorineural hearing loss: mechanisms, therapeutics, and translational prospects
  3. Intensive Care Medicine, 2019 -- Revised Terminology for Delirium and Acute Encephalopathy: A Consensus from Ten Medical Societies
  4. A Cadaveric Study on the Endoscopic Supraorbital Keyhole Approach for Implantation of the Olfactory Bulb versus the Olfactory Tract
  5. Summary of Japanese clinical practice guidelines 2025 for the management of olfactory dysfunction - ScienceDirect
  6. The efficacy of olfactory training in improving olfactory function: a meta-analysis | European Archives of Oto-Rhino-Laryngology | Springer Nature Link
  7. Topical platelet-rich plasma as a possible treatment for olfactory dysfunction-A randomized controlled trial - PubMed
  8. Summary of Japanese clinical practice guidelines 2025 for the management of olfactory dysfunction - ScienceDirect
  9. The efficacy of olfactory training in improving olfactory function: a meta-analysis | European Archives of Oto-Rhino-Laryngology | Springer Nature Link
  10. Topical platelet-rich plasma as a possible treatment for olfactory dysfunction-A randomized controlled trial - PubMed

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