Pulmonary cryptococcosis with cavitation in an immunocompetent child: a case report and literature review
By
Wen Zhang
Guohua Yao
Haoyi Wang
Juxia Xi
Cuian Ma
Botao Wei
Tongqiang Zhang
June 9, 2026
Clinical Scorecard: Cavitary Pulmonary Cryptococcosis in an Immunocompetent Pediatric Patient: A Case Study and Review of Existing Literature
At a Glance
Category Detail
Condition Key Mechanisms Inhalation of airborne Cryptococcus spores from environmental sources. Target Population Care Setting
Key Highlights
Increased incidence of PC among non-HIV-infected individuals. Non-specific respiratory symptoms complicate diagnosis. Case study of a 14-year-old girl with cavitary PC. Follow-up showed near-complete resolution of pulmonary lesions. Guideline-Based Recommendations
Diagnosis
Perform cryptococcus-related investigations in pediatric patients with pulmonary cavitation and non-specific respiratory symptoms. Management
Administer antifungal therapy, such as oral fluconazole, tailored to immune status and disease severity. Monitoring & Follow-up
Regular follow-up imaging to assess resolution of pulmonary lesions. Risks
Delayed recognition may lead to progression to disseminated infection. Patient & Prescribing Data
Fluconazole at 6 mg/kg/day was effective in managing the condition.
Clinical Best Practices
Consider PC in differential diagnosis for pediatric patients with cavitary lung lesions. Related Resources & Content
