Multimodal MRI reveals three-tiered pathological co-alterations in prolonged disorders of consciousness: structural disconnection, network disintegration, and regional hyperconnectivity - Scorecard - MDSpire

Multimodal MRI reveals three-tiered pathological co-alterations in prolonged disorders of consciousness: structural disconnection, network disintegration, and regional hyperconnectivity

By
Xiyong Wang
Yi Yin
Xianbin Wang
Shuang Wu
June 9, 2026
0 min

Frontiers In Neurology

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Clinical Scorecard: Multimodal MRI Analysis Identifies Three Levels of Pathological Changes in Prolonged Disorders of Consciousness: Structural Disconnection, Network Disruption, and Regional Hyperconnectivity

At a Glance

Category	Detail
Condition
Key Mechanisms	Structural disconnection, network disruption, regional hyperconnectivity linked to specific findings.
Target Population
Care Setting