To measure serum 25-hydroxyvitamin D (25[OH]D) concentrations in pregnant women and their newborns and to explore potential associations between vitamin D levels and maternal and neonatal factors.
Key Findings:
Median maternal serum vitamin D level was 9.86 ng/mL; 99.7% of samples were below 20 ng/mL.
Median cord blood serum vitamin D level was 10.12 ng/mL; 99.5% of samples were below 20 ng/mL.
Only 19.1% of women reported vitamin D supplementation during pregnancy.
Maternal and cord blood vitamin D levels were positively associated (Spearman’s rho = 0.357, p < 0.001).
Vitamin D levels were higher in women and neonates born in summer compared to winter.
Interpretation:
Vitamin D insufficiency was highly prevalent among pregnant women and newborns in this Jordanian cohort.
Limitations:
The study was limited to a single hospital, which may affect generalizability.
Exclusion of women with chronic medical conditions may limit understanding of vitamin D status in the broader population.
Conclusion:
Further evaluation of targeted screening, appropriate supplementation strategies, and public health interventions is warranted.
