Clinical correlation between platelet parameters and coronary artery lesions in pediatric Kawasaki disease - Summary - MDSpire

Clinical correlation between platelet parameters and coronary artery lesions in pediatric Kawasaki disease

  • By

  • Yujia Ji

  • Xia Chen

  • Lizhi Jiang

  • Chao Li

  • June 9, 2026

  • 0 min

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Objective:

To investigate the clinical correlation between the occurrence of coronary artery lesions and platelet levels in children with Kawasaki disease.

Key Findings:
  • Platelet parameters in KD children were significantly higher than in healthy controls (all P < 0.05).
  • The lesion group had significantly higher platelet parameters compared to the non-lesion group (all P < 0.05).
  • The Harada score was significantly higher in the lesion group than in the non-lesion group (P < 0.05).
  • Multivariate binary logistic regression showed significant correlations between PLT, MPV, PCT, PDW and coronary artery lesions (P < 0.05).
Interpretation:

Limitations:
  • The study is retrospective and may be subject to selection bias.
  • No a priori sample size calculation was performed.
Conclusion:

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