Evaluating the Long-Term Effects of COVID-19 on Various Sensory Functions - Summary - MDSpire

Evaluating the Long-Term Effects of COVID-19 on Various Sensory Functions

  • By

  • Ahmad Odeh

  • Veronica L. Formanek

  • Christina Smith

  • Nidhi Jha

  • Junichi Tajino

  • Jessica H. Lewis

  • Lauren Gastineau

  • Shivani Patel

  • Songzhu Zhao

  • Lai Wei

  • Aaron C. Moberly

  • Daniel M. Merfeld

  • Christopher T. Simons

  • Megan J. Kobel

  • Kai Zhao

  • February 27, 2026

  • 0 min

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Objective:

To determine the long-term impact of COVID-19 on sensory functions, including smell, taste, chemesthesis, hearing, and vestibular/balance function, and their significance in daily life.

Key Findings:
  • A significant proportion of COVID-19 patients (quantify) report long-term sensory dysfunctions, particularly in smell and taste.
  • Neurological symptoms, including sensory dysfunction, persist in 73-76% of patients 60-180 days post-diagnosis.
  • The study found evidence of both peripheral and central mechanisms contributing to sensory dysfunction.
Interpretation:

The findings suggest that COVID-19 has a lasting impact on sensory functions, which may involve complex mechanisms beyond initial infection, with implications for patient care.

Limitations:
  • The study's exploratory nature limits the generalizability of results.
  • No post-hoc corrections for multiple comparisons were applied, which may affect the interpretation of findings.
  • Potential biases in recruitment may affect the results.
Conclusion:

COVID-19 can lead to significant long-term sensory dysfunctions, necessitating further research to understand the underlying mechanisms and potential treatments, particularly in areas such as rehabilitation.

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