To quantify medication restart frequency and timing during care transitions, identify patient and system factors associated with restart, and examine restart associations with emergency department visits and readmissions.
Key Findings:
Deprescribing interventions showed a 14% reduction in total medications at SNF discharge and a 15% reduction maintained 90 days post-discharge.
Adverse drug withdrawal events accounted for 1.8% to 19.7% of all adverse drug events, with no significant difference between intervention and control groups.
Frequent medication restarts may indicate inadequate patient education, poor care coordination, or unresolved symptoms.
Interpretation:
Remove or rephrase to avoid unsupported conclusions.
Limitations:
The study did not independently document switches between drug classes or by indication.
Missing data due to loss to follow-up in the parent trials was not imputed.
Conclusion:
Revise to reflect only findings without implications.
