Pulmonary cryptococcosis with cavitation in an immunocompetent child: a case report and literature review
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By
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Wen Zhang
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Guohua Yao
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Haoyi Wang
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Juxia Xi
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Cuian Ma
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Botao Wei
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Tongqiang Zhang
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June 9, 2026
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Objective:
To enhance clinical awareness of pulmonary cryptococcosis (PC) in immunocompetent individuals.
Key Findings:
- PC can occur in immunocompetent children, presenting with non-specific respiratory symptoms.
- The diagnosis was confirmed through positive antigen tests and targeted next-generation sequencing.
- The patient showed near-complete resolution of pulmonary lesions after treatment.
Interpretation:
Prompt diagnosis and individualized treatment strategies are crucial for managing pulmonary cryptococcosis in pediatric patients.
Limitations:
- Epidemiological data on PC in pediatric populations, especially in developing countries, are limited.
- The study is based on a single case, which may not represent broader trends.
Conclusion:
Cryptococcus-related investigations should be conducted in pediatric patients with pulmonary cavitation and non-specific respiratory symptoms.
