Prepubertal Growth Trajectory and Pubertal Onset - Summary - MDSpire

Prepubertal Growth Trajectory and Pubertal Onset

  • By

  • Rui Deng

  • Weiqin Li

  • Jiali Duan

  • Tianshu Feng

  • Liumei Wei

  • Xingxiu Li

  • Junhong Leng

  • Xijie Wang

  • Bin Dong

  • Susan M. Sawyer

  • June 9, 2026

  • 0 min

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Objective:

To characterize BMI trajectories from birth across the first decade, examine the associations of cumulative exposure to different levels of adiposity with pubertal timing, and identify potential sensitive periods for preventive intervention.

Key Findings:
  • Higher BMI is associated with earlier pubertal onset.
  • Cumulative exposure to adiposity may better predict pubertal timing than single measurements.
  • Rapid BMI increases may relate to earlier pubertal onset, but specific sensitive periods remain unclear.
Interpretation:

Limitations:
  • Most pediatric studies have relied on short-term BMI measurements.
  • Few studies have tracked growth from birth to puberty comprehensively.
  • The absence of studies identifying sensitive periods for BMI increase in relation to pubertal timing.
Conclusion:

Original Source(s)

Prepubertal Growth Trajectory and Pubertal Onset

  • by Rui Deng, Weiqin Li, Jiali Duan, Tianshu Feng, Liumei Wei, Xingxiu Li, Junhong Leng, Xijie Wang, Bin Dong, Susan M. Sawyer

  • June 9, 2026

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