Association between maternal PAH exposure and immune-inflammatory indices during pregnancy - Takeaways - MDSpire

Association between maternal PAH exposure and immune-inflammatory indices during pregnancy

  • By

  • Lin Tao

  • Yi Zhang

  • Yuan-zhong Zhou

  • Xubo Shen

  • June 9, 2026

  • 0 min

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  • 1

    The study included 2581 pregnant women to explore the association between maternal PAH exposure and immune-inflammatory indices.

  • 2

    PAH metabolites were measured in urine, revealing correlations with various immune-inflammatory markers during pregnancy.

  • 3

    Key metabolites negatively correlated with white blood cell count and neutrophil to lymphocyte ratio, while positively correlating with systemic immune inflammation index.

  • 4

    Bayesian kernel machine regression models indicated non-linear associations between PAH metabolites and immune indices.

  • 5

    The findings suggest maternal PAH exposure during pregnancy is linked to alterations in immune-inflammatory indices.

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