Fontan haemodynamics in adults with obesity compared with overweight and normal body mass index: a retrospective invasive exercise study

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Obesity significantly impacts exercise haemodynamics and capacity in adults post-Fontan, with 18 patients classified as obese in the study.
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Patients with obesity exhibited lower peak oxygen consumption (VO2) compared to those with overweight/normal BMI during exercise testing.
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At rest, individuals with obesity had higher systemic flow, pulmonary artery pressure, and pulmonary artery wedge pressure than those with normal BMI.
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During exercise, obese patients also showed increased pulmonary artery pressure and wedge pressure, alongside decreased arterial oxygen saturation.
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Further research is needed to determine if treating obesity in Fontan patients can improve their haemodynamics and overall health outcomes.

European Journal Of Preventive Cardiology

by Derek N Opp, C Charles Jain, Alexander C Egbe, Barry A Borlaug, Yogesh V Reddy, Heidi M Connolly, Kyla M Lara-Breitinger, Rachael Cordina, William R Miranda
September 28, 2024

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