Association of estimated glomerular filtration rate and in-hospital mortality in patients hospitalized for heart failure: a retrospective cohort study - Takeaways - MDSpire

Association of estimated glomerular filtration rate and in-hospital mortality in patients hospitalized for heart failure: a retrospective cohort study

  • By

  • Yueriyeti Aierken

  • Gulburak Taalaibek kyzy

  • Meng Wei

  • Yanmei Lu

  • Jianghua Zhang

  • Zukela Tuerhong

  • Baopeng Tang

  • Xianhui Zhou

  • June 9, 2026

  • 0 min

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  • 1

    The study analyzed 14,591 heart failure patients to evaluate the impact of estimated glomerular filtration rate (eGFR) on in-hospital mortality.

  • 2

    In-hospital mortality rates increased progressively across eGFR categories, with rates of 5.77% to 11.72% for varying eGFR levels.

  • 3

    eGFR levels of 45–59 and 30–44 mL/min/1.73 m2 were independently associated with higher in-hospital mortality risk after full covariate adjustment.

  • 4

    Patients with eGFR < 60 mL/min/1.73 m2 had a 37% higher risk of in-hospital mortality, particularly in NYHA class III and IV.

  • 5

    A nonlinear association was found between eGFR and in-hospital mortality risk, with a critical inflection point at approximately 60 mL/min/1.73 m2.

Original Source(s)

Association of estimated glomerular filtration rate and in-hospital mortality in patients hospitalized for heart failure: a retrospective cohort study

  • by Yueriyeti Aierken, Gulburak Taalaibek kyzy, Meng Wei, Yanmei Lu, Jianghua Zhang, Zukela Tuerhong, Baopeng Tang, Xianhui Zhou

  • June 9, 2026

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