Optimizing gastric cancer treatment: the role of LODDs in lymph node staging - Takeaways - MDSpire

Optimizing gastric cancer treatment: the role of LODDs in lymph node staging

  • By

  • Zhao Hao

  • Haiyan Niu

  • Yuebo Bi

  • Qimin Sun

  • Wenjun Yang

  • June 9, 2026

  • 0 min

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  • 1

    Gastric cancer is a prevalent malignancy with poor prognosis, necessitating accurate lymph node staging for improved treatment outcomes.

  • 2

    This study compares the prognostic value of AJCC N stage, lymph node ratio (LNR), and log odds of positive lymph nodes (LODDs) in gastric adenocarcinoma.

  • 3

    LODDs demonstrated superior predictive performance for overall survival compared to AJCC-N and LNR in gastric adenocarcinoma patients.

  • 4

    A nomogram based on LODDs and other clinical factors showed good calibration and clinical net benefit for individualized prognostic assessment.

  • 5

    Further validation of the LODDs-based nomogram is needed in well-defined lymphadenectomy cohorts to enhance its clinical utility.

Original Source(s)

Optimizing gastric cancer treatment: the role of LODDs in lymph node staging

  • by Zhao Hao, Haiyan Niu, Yuebo Bi, Qimin Sun, Wenjun Yang

  • June 9, 2026

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