Electroacupuncture at LI11 and SP10 is associated with alleviation of acute urticaria-like reactions in passive cutaneous anaphylaxis: an exploratory analysis of complement-related proteins and multiscale omics - Takeaways - MDSpire

Electroacupuncture at LI11 and SP10 is associated with alleviation of acute urticaria-like reactions in passive cutaneous anaphylaxis: an exploratory analysis of complement-related proteins and multiscale omics

  • By

  • LinXin You

  • Yan Zhao

  • JingYu Zhang

  • SiJia Li

  • JiQuan Li

  • June 8, 2026

  • 0 min

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  • 1

    Electroacupuncture at LI11 and SP10 was studied for its effects on acute urticaria-like symptoms in a passive cutaneous anaphylaxis model.

  • 2

    The treatment resulted in reduced wheal areas, decreased scratching frequencies, and lower cutaneous vascular permeability in the model.

  • 3

    Multi-omics profiling indicated alterations in lipid and amino acid metabolic pathways associated with the electroacupuncture intervention.

  • 4

    Decreased expression of C3a/C5a and their receptors was observed in skin tissues following electroacupuncture treatment.

  • 5

    The study provides exploratory data on molecular changes linked to electroacupuncture in an acute allergic model.

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