Association between H. pylori infection status, UBT-derived DOB level, and colorectal polyp detection - Takeaways - MDSpire

Association between H. pylori infection status, UBT-derived DOB level, and colorectal polyp detection

  • By

  • Yu Zhou

  • Ge Yu

  • Zhigang Huang

  • Rong Wan

  • June 9, 2026

  • 0 min

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  • 1

    Helicobacter pylori positivity was associated with a higher detection rate of colorectal polyps compared to H. pylori-negative individuals.

  • 2

    In the unmatched cohort, H. pylori-positive participants had an odds ratio of 4.05 for colorectal polyp detection after multivariable adjustment.

  • 3

    Higher urea breath test-derived delta over baseline values correlated with increased odds of colorectal polyp detection.

  • 4

    Adenomatous polyps were detected more frequently in H. pylori-positive participants, with a significant difference in detection rates.

  • 5

    The findings suggest a need for validation in larger multicenter studies due to the limited discriminatory ability of DOB alone.

Original Source(s)

Association between H. pylori infection status, UBT-derived DOB level, and colorectal polyp detection

  • by Yu Zhou, Ge Yu, Zhigang Huang, Rong Wan

  • June 9, 2026

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