Associations between maternal thyroid hormones and neonatal outcomes during pregnancy - Takeaways - MDSpire

Associations between maternal thyroid hormones and neonatal outcomes during pregnancy

  • By

  • Lin Tao

  • Yi Zhang

  • Yuan-zhong Zhou

  • Xubo Shen

  • June 8, 2026

  • 0 min

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  • 1

    The study included 2,884 pregnant women across three trimesters to analyze maternal thyroid hormone levels and neonatal outcomes.

  • 2

    Maternal TSH levels increased gradually, while TT3 peaked in mid-pregnancy and FT3/FT4 levels declined continuously throughout gestation.

  • 3

    Weak correlations were found between maternal thyroid hormones and neonatal outcomes, with trimester- and sex-specific associations identified.

  • 4

    RCS analysis revealed dose-response relationships with thyroid hormones and neonatal outcomes, varying by pregnancy stage and sex.

  • 5

    The study highlights the importance of monitoring gestational thyroid function to understand its impact on maternal and neonatal health.

Original Source(s)

Associations between maternal thyroid hormones and neonatal outcomes during pregnancy

  • by Lin Tao, Yi Zhang, Yuan-zhong Zhou, Xubo Shen

  • June 8, 2026

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