Next-generation sequencing (NGS) is being explored for pathogen detection, outbreak investigation, and antimicrobial resistance surveillance in clinical microbiology.
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Nanopore sequencing offers flexibility and long-read capabilities, improving pathogen characterization and integration into routine clinical workflows.
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Implementation of nanopore sequencing in clinical laboratories is feasible, requiring expertise in laboratory-developed tests and robust validation processes.
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NGS is unlikely to replace traditional methods but may complement them by enhancing sensitivity, specificity, and turnaround time in diagnostics.
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Nanopore sequencing supports outbreak detection and public health surveillance by providing detailed genomic data for epidemiology and resistance monitoring.