Long-term impact of a quality improvement program on unplanned extubation and clinical outcomes in adult intensive care units: a 24-year single-center observational study - Takeaways - MDSpire

Long-term impact of a quality improvement program on unplanned extubation and clinical outcomes in adult intensive care units: a 24-year single-center observational study

  • By

  • I-Lin Tsai

  • Chun-Wei Kuo

  • Ching-Min Wang

  • Chen-Wei Wu

  • Chin-Ming Chen

  • June 8, 2026

  • 0 min

Share

  • 1

    A continuous quality improvement program significantly reduced unplanned extubation rates from 6.82 to 0.65 per 100 ventilated patients over 24 years.

  • 2

    Among first-episode unplanned extubation patients, 52.5% required reintubation within 48 hours, leading to longer ICU stays and increased mortality.

  • 3

    Factors associated with reintubation included higher APACHE II scores, elevated respiratory rates, and not undergoing ventilator weaning at the time of unplanned extubation.

  • 4

    Mortality after unplanned extubation was linked to higher APACHE II scores, liver cirrhosis, malignancy, and prolonged ICU stays.

  • 5

    The study highlights the importance of early risk stratification and targeted monitoring for high-risk patients following unplanned extubation.

Original Source(s)

Long-term impact of a quality improvement program on unplanned extubation and clinical outcomes in adult intensive care units: a 24-year single-center observational study

  • by I-Lin Tsai, Chun-Wei Kuo, Ching-Min Wang, Chen-Wei Wu, Chin-Ming Chen

  • June 8, 2026

Related Content

Case Report: Individualized management of tuberous sclerosis complex-associated lymphangioleiomyomatosis

Long-term protective potency of AAV vector-based SARS-CoV-2 prophylaxis in mice and non-human primates

First-line serplulimab plus chemotherapy versus chemotherapy alone in small-cell lung cancer patients with brain metastases: a multicenter, prospective cohort study