Complement receptor 2 downregulation is associated with mortality in Staphylococcus aureus sepsis in both mice and humans

• by Pradeep Kumar Kopparapu, Meghshree Deshmukh, Santhilal Subhash, Majd Mohammad, Zhicheng Hu, Anders Jarneborn, Muhammad Arif, Marcela Pekna, Lars Ljungström, Gunnar Jacobsson, Ola Grimsholm, Tao Jin

• July 9, 2026

Caspases and programmed cell death in sepsis: mechanisms, pathophysiology, and therapeutic targets

• by Haibei He, Xiuli Xie, Lisui Zhou, Yumeng Lin, Aijun Liu, Peng Guo, Yu Zhu, Yu Tang, Zhongyu Han, Yi Wang, Haoran Chen

• July 17, 2026

Association between clinical characteristics within 6 h of ICU admission and 30-day mortality risk in immunocompromised sepsis patients: development and validation of a machine learning model based on the MIMIC-IV database

• by Zhipeng Cheng, Xiuqing Ma, Weiying Duan, Zeyu Mou, Zhixin Liang

• July 13, 2026

Does High PCT Warrant Longer Therapy?

In a planned BALANCE analysis, elevated day 7 procalcitonin was associated with higher mortality, but the small subgroup analysis found no evidence that extending antibiotics from 7 to 14 days improved outcomes.

• by Andrea Surnit

• July 15, 2026

• 4 min