Safety and activity of RO7300490, a bispecific CD40 agonist targeted to fibroblast activation protein, in patients with advanced solid tumors: a single-arm, multicenter, first-in-human, phase 1 trial - Poll - MDSpire

Safety and activity of RO7300490, a bispecific CD40 agonist targeted to fibroblast activation protein, in patients with advanced solid tumors: a single-arm, multicenter, first-in-human, phase 1 trial

  • By

  • Ignacio Melero

  • Bernhard Reis

  • Corinne Rusterholz

  • Alexandra Epp

  • Nicole A. Kratochwil

  • Chun Wu

  • Michael Hettich

  • Georgios Kazantzidis

  • Natascha Rieder

  • Petra C. Schwalie

  • Solveig Badillo

  • Nadine Kumpesa

  • Andreas Thommen

  • Danielle J. Vugts

  • Victor Moreno

  • Julia Lostes Bardaji

  • Eduardo Castanon Alvarez

  • Carlos E. de Andrea

  • Iben Spanggaard

  • Dae Ho Lee

  • James Spicer

  • Fiona Thistlethwaite

  • Do-Youn Oh

  • Antoine Hollebecque

  • Olivera Cirovic

  • Stefan N. Symeonides

  • May 1, 2026

  • 0 min

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