Integrated post-GWAS, single-cell, and functional analyses prioritize TCTN2 at an osteoarthritis locus associated with innate immunity-related cartilage remodeling

• by Changchun Lu, Lei Wang, Xinqi Cao, Kun Zhao, Nuo Yin, Dong Zhang

• July 6, 2026

CAA Use Tied to Higher Arthroplasty Risk

In a UK cohort, patients with osteoarthritis who initiated centrally acting analgesics had a higher hazard of knee or hip replacement than those who initiated SSRIs, though residual confounding by pain severity remains a key limitation.

• by Andrea Surnit

• June 1, 2026

• 6 min

Radon balneotherapy in rheumatologic diseases: potential mechanisms and implications for cardiovascular autonomic control and inflammation

• by Gabriel D. Rodrigues, Earric Lee, Benoit Dugué, Christian Hanshans, Maria Chiara Maccarone, Konstantinos Triantafyllias, Arnulf Hartl, Eugenijus Kaniusas, Sabrina Mörkl, Thomas E. Schmid, Goda-Camille Mickeviciute, Hannes Untner, Werner Klingler, Martin Offenbächer

• June 24, 2026

Top 10 States With Rising Demand for Physicians

These 10 states report physician shortages, projected physician supply gaps, or physician-to-population ratios below national benchmarks.

• by mdspire news news staff

• May 28, 2026

• 3 min