CAA Use Tied to Higher Arthroplasty Risk - Quiz - MDSpire

CAA Use Tied to Higher Arthroplasty Risk

In a UK cohort, patients with osteoarthritis who initiated centrally acting analgesics had a higher hazard of knee or hip replacement than those who initiated SSRIs, though residual confounding by pain severity remains a key limitation.

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  • Andrea Surnit

  • June 1, 2026

  • 6 min

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CAA Use Tied to Higher Arthroplasty Risk

  • by Andrea Surnit

  • June 1, 2026

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