Targeting the synovial engine: next-generation engineered immune cells to eradicate pathogenic FLS in rheumatoid arthritis, with safety-first, selective designs

• by Ashik Anil Mathew, Arulkumaran Rithvik, Mahaboobkhan Rasool

• July 9, 2026

JAK Monotherapy Shows Efficacy in RA Review

A systematic review found Janus kinase inhibitor monotherapy improved outcomes vs methotrexate or placebo, but direct comparisons with combination therapy were limited.

• by Andrea Surnit

• May 22, 2026

• 4 min

Outcomes and associated factors of revision procedures after failed total ankle arthroplasty: a comparative cohort analysis

• by Kathrin Pfahl, Julia Eder, Dominic Simon, Gautier Beckers, Boris Michael Holzapfel, Markus Walther

• April 17, 2026

IL-34-mediated fibroblast-like synoviocyte-macrophage crosstalk drives bone erosion in rheumatoid arthritis through RANKL-dependent osteoclastogenesis

• by Xin Li, Yurou Yang, Shuao Zhang, Yujing Cai, Aiqi Wang, Na Xu

• June 17, 2026