Durable response to ALK inhibition in low-allele-frequency SPTBN1–ALK–rearranged gastric cancer followed by lineage plasticity–mediated resistance: a case report - Quiz - MDSpire

Sustained Response to ALK Inhibition in Gastric Cancer with Low-Frequency SPTBN1–ALK Rearrangement and Subsequent Resistance via Lineage Plasticity: A Case Study

  • By

  • Zihua Guan

  • Jiao Liu

  • Wenlu Yu

  • Xu Wang

  • Xinmei Zhang

  • July 21, 2026

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