FDA Signals New Testosterone Pathway

• by Kathryn Wighton

• April 16, 2026

TOFA may drive weight loss without reducing food intake

The oral compound increased energy expenditure, reduced fat mass, and improved metabolic measures in male mouse models.

• by Andrea Surnit

• August 27, 2026

• 4 min

GLP-1 RAs Associated With Small ION Risk Increase

In an observational US target trial emulation, glucagon-like peptide-1 receptor agonist initiation was associated with about 3 to 4 more ischemic optic neuropathy cases per 10,000 patients over 18 months than two comparator drug classes.

• by Andrea Surnit

• July 13, 2026

• 5 min

Are GLP-1s Linked to Optic Neuropathy?

A nationwide Swedish cohort found a higher relative risk of anterior ischemic optic neuropathy among GLP-1 receptor agonist users, but the overall risks were low.

• by Andrea Surnit

• July 14, 2026

• 3 min