Novartis and BMS Pause Autoimmune CAR T Trials Over Safety Concerns

• September 16, 2026

Dysregulation of U12-Type Splicing in Lupus Neutrophils

• by Luz P. Blanco, Binod Regmi, Carmelo Carmona-Rivera, Yudong Liu, Xiantao Wang, Philip M. Carlucci, Monica M. Jackson, Zerai Manna, Sarfaraz Hasni, Markus Hafner, Hong-Wei Sun, Mariana J. Kaplan

• July 1, 2026

DNA (cytosine-5)-methyltransferase 3A (Dnmt3a) mutations limit normal and autoreactive CD4+ T follicular helper responses and attenuate T cell-driven joint inflammation

• by Yunbing Shen, Sanjaykumar Boddul, Zhaojun Li, Zsolt Kasza, Marlene Schülein, Bruno Raposo, Karine Chemin, Per-Johan Jakobsson, Alexander Espinosa, Lars Klareskog, Fredrik Wermeling

• June 29, 2026

FDA Approves Atacicept for IgA Nephropathy

The approval was based on reduced proteinuria, and an ongoing trial is required to determine whether atacicept slows long-term kidney function decline.

• by Kathryn Wighton

• July 7, 2026

• 3 min