Early postoperative orthostatic intolerance: pathophysiology and clinical implications

• by Girish P Joshi, Dileep N Lobo, Henrik Kehlet

• June 6, 2025

Obesity Not Associated With Worse Long-Term TAR Outcomes

A long-term cohort study found that obesity was not associated with worse patient-reported outcomes or higher reoperation rates following total ankle replacement in optimized surgical candidates.

• by Kathryn Wighton

• May 6, 2026

• 4 min

Hidden Pain After Mastectomy?

Chronic postsurgical pain affects many patients but is often underdiagnosed and undertreated.

• by Brett Kelman, Amy Maxmen

• April 6, 2026

• 10 min

CAA Use Tied to Higher Arthroplasty Risk

In a UK cohort, patients with osteoarthritis who initiated centrally acting analgesics had a higher hazard of knee or hip replacement than those who initiated SSRIs, though residual confounding by pain severity remains a key limitation.

• by Andrea Surnit

• June 1, 2026

• 6 min