Clinical Report: First Description of Peritoneal Dialysis-Associated Peritonitis Due to Pseudomonas fulva

Overview

This report details the first case of peritoneal dialysis-associated peritonitis caused by Pseudomonas fulva in a 67-year-old male patient. The infection was successfully treated with cefotaxime, highlighting the importance of accurate pathogen identification in clinical management.

Background

Pseudomonas fulva is a rare Gram-negative bacterium that has been linked to various infections, yet its role in peritoneal dialysis-related peritonitis has not been previously documented. Peritoneal dialysis is a common treatment for end-stage renal disease, but peritonitis remains a significant complication that can lead to technique failure and increased mortality. Understanding the pathogens involved in such infections is crucial for effective treatment and patient outcomes.

Data Highlights

The patient presented with acute abdominal pain and was diagnosed with peritoneal dialysis-related peritonitis. Laboratory tests revealed a WBC count of 15.61 × 10^9/L and positive cultures for P. fulva.

Key Findings

• The patient was a 67-year-old male with multiple comorbidities, including end-stage renal disease.
• P. fulva was accurately identified using MALDI-TOF MS and 16S rRNA sequencing.
• The infection was treated successfully with cefotaxime.
• This case represents the first documented instance of peritoneal dialysis-associated peritonitis due to P. fulva.
• Accurate identification of pathogens is essential for effective management of peritoneal dialysis-related infections.

Clinical Implications

Clinicians should be aware of the potential for Pseudomonas fulva to cause peritoneal dialysis-related peritonitis, particularly in patients with complex medical histories. Rapid identification and appropriate antibiotic therapy are critical for improving patient outcomes in such cases.

Conclusion

The identification of Pseudomonas fulva as a causative agent of peritoneal dialysis-associated peritonitis underscores the need for vigilance in pathogen detection and tailored treatment strategies.

Related Resources & Content

1. Frontiers | First Report of Peritoneal Dialysis-Related Peritonitis Caused by Pseudomonas fulva
2. ISPD peritonitis guideline recommendations: 2022 update on prevention and treatment
3. Infection — Fungal Peritonitis in Patients Undergoing Peritoneal Dialysis: A Five-Year Analysis from a Center in Northern China
4. Open Forum Infectious Diseases — Impact of Remote Cholecystectomy on Clinical Outcomes Following Pseudomonas aeruginosa Bloodstream Infection
5. Frontiers in Surgery — Case Report: Multidisciplinary collaboration for the treatment of severe necrotizing fasciitis in the perineum caused by rectal cancer perforation
6. Infection — Identifying Risk Factors and Outcomes of Bloodstream Infections Due to Pseudomonas aeruginosa in Hematology Patients: A Retrospective Cohort Analysis from a Single Center
7. ISPD peritonitis guideline recommendations: 2022 update on prevention and treatment - Philip Kam-Tao Li, Kai Ming Chow, Yeoungjee Cho, Stanley Fan, Ana E Figueiredo, Tess Harris, Talerngsak Kanjanabuch, Yong-Lim Kim, Magdalena Madero, Jolanta Malyszko, Rajnish Mehrotra, Ikechi G Okpechi, Jeff Perl, Beth Piraino, Naomi Runnegar, Isaac Teitelbaum, Jennifer Ka-Wah Wong, Xueqing Yu, David W Johnson, 2022
8. The association between empirical antibiotic regimens and the outcome of peritoneal dialysis-related peritonitis: a multi-center, large-scale cohort study | Journal of Nephrology | Springer Nature Link
9. Frontiers | First Report of Peritoneal Dialysis-Related Peritonitis Caused by Pseudomonas fulva