Understanding access to novel high-cost cancer therapies across Canada: a national survey of pediatric oncology providers - Report - MDSpire

Understanding access to novel high-cost cancer therapies across Canada: a national survey of pediatric oncology providers

  • By

  • Kriti Kumar

  • Avram Denburg

  • Celine Cressman

  • Derek S. Tsang

  • Marcel Romanick

  • Myanca Rodrigues

  • Paul J. Gibson

  • May 20, 2026

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Clinical Report: Access to High-Expense Cancer Treatments for Children in Canada

Overview

This study identifies significant disparities in access to high-cost cancer therapies for children in Canada, highlighting barriers such as travel and funding issues. Recommendations for policy changes include universal funding and the establishment of specialized treatment centers.

Background

Access to innovative cancer therapies for children in Canada is often inequitable due to the high costs and lack of public funding for certain treatments. This situation necessitates a better understanding of the barriers faced by pediatric oncology providers and their patients. Addressing these disparities is crucial for improving treatment outcomes and ensuring that all children have access to effective therapies.

Data Highlights

TherapyAccess Rate (%)Respondents (n)
Blinatumomab8935
Larotrectinib7927
Proton Beam Therapy59.230
Tisagenlecleucel9430

Key Findings

  • Access rates for blinatumomab, larotrectinib, PBT, and tisagenlecleucel were reported at 89%, 79%, 59.2%, and 94%, respectively.
  • Key barriers included patient/family inability to travel and the economic impact of travel.
  • The high cost of larotrectinib was identified as a significant barrier to access.
  • Most respondents were pediatric medical oncologists, indicating a specialized focus in the survey.
  • Universal funding and simplified approval processes are recommended to improve access.

Clinical Implications

Healthcare providers should be aware of the disparities in access to high-cost cancer therapies and advocate for policy changes that promote equitable access. Understanding the barriers faced by families can help in developing supportive measures to facilitate treatment access.

Conclusion

The findings underscore the need for systemic changes in Canada to ensure equitable access to high-cost cancer therapies for children. Addressing these barriers is essential for improving treatment outcomes in pediatric oncology.

Related Resources & Content

  1. American Cancer Society, The ASCO Post, 2016 -- New American Cancer Society Report Reveals Gaps, Identifies Unique Barriers in Pediatric Cancer Research
  2. American Cancer Society, The ASCO Post, 2020 -- Precision Medicine Is Becoming a Reality for Pediatric Patients With Cancer
  3. Children’s Oncology Group, The ASCO Post, 2016 -- Pediatric Oncology Groups Endorse Ethical Framework for Rationing Scarce Drugs
  4. Journal of Neuro-Oncology, 2023 -- Management Approaches for Recurrent Pediatric High-Grade Glioma: Insights from a Pan-European Survey
  5. New England Journal of Medicine, 2023 -- Dabrafenib plus Trametinib in Pediatric Glioma with BRAF V600 Mutations
  6. ScienceDirect, 2025 -- Kymriah Real-World Effectiveness and Functional Persistence in Acute Lymphoblastic Leukemia (ALL)
  7. ASTRO, Model Policies -- Proton Beam Therapy (PBT)
  8. Dabrafenib plus Trametinib in Pediatric Glioma with BRAF V600 Mutations | New England Journal of Medicine
  9. Kymriah Real-World Effectiveness and Functional Persistence in Acute Lymphoblastic Leukemia (ALL) (KareALL): A Retrospective Analysis of the Effect of Current Tisagenlecleucel (tisa-cel) Manufacturing in Pediatric and Young Adult Patients (pts) with ALL - ScienceDirect
  10. ASTRO Model PoliciesPROTON BEAM THERAPY (PBT)This Model Policy* addresses coverage for Proton Beam Therapy.DESCRIPTIONProton Beam Therapy (PBT) is a technology for delivering conformal external beam radiation with positively charged subatomic

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