Comparison of aortoiliac disease stenting patency using balloon-expandable, self-expanding, and covered stents - Report - MDSpire

Comparison of aortoiliac disease stenting patency using balloon-expandable, self-expanding, and covered stents

  • By

  • Ali A. Hasnie

  • Tonga Nfor

  • James O. Adefisoye

  • Kelly Magee

  • M. Fuad Jan

  • Mark W. Mewissen

  • Tanvir K. Bajwa

  • Babak Haddadian

  • May 13, 2026

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Clinical Report: Evaluation of Patency Rates in Aortoiliac Disease Stenting

Overview

This study evaluates the primary patency rates of balloon-expandable, self-expanding, and covered stents in patients with aortoiliac disease. Results indicate that while balloon-expandable stents showed a slight advantage at one year, this difference did not persist at three years, suggesting stent selection should be based on other factors.

Background

Peripheral arterial disease (PAD) affects millions in the U.S., with a significant proportion involving the iliac arteries. Effective treatment options are critical as the incidence of PAD is expected to rise with an aging population. Understanding the comparative effectiveness of different stent types can guide clinical decision-making in managing aortoiliac disease.

Data Highlights

Stent Type1-Year Patency Rate3-Year Patency Rate
Balloon-Expandable98.4%Not significant
Self-Expanding97.1%Not significant
Covered96.3%Not significant

Key Findings

  • The majority of stents implanted were balloon-expandable (58%).
  • Technical success rates exceeded 99% across all stent types.
  • One-year primary patency rates were 98.4% for balloon-expandable, 97.1% for self-expanding, and 96.3% for covered stents (P = 0.03).
  • No significant differences in three-year primary patency rates were observed (P = 0.17).
  • Stent selection should consider cost, lesion characteristics, and operator judgment rather than solely long-term patency outcomes.

Clinical Implications

Clinicians should weigh the advantages and limitations of each stent type when treating aortoiliac disease. Given the lack of significant long-term differences in patency, factors such as cost and individual patient anatomy may play a more critical role in stent selection.

Conclusion

This study underscores the importance of individualized stent selection in aortoiliac interventions, as long-term patency rates do not significantly differ among stent types.

References

  1. American College of Cardiology, 2024 ACC/AHA/Multisociety Guideline for Lower Extremity PAD: Key Points
  2. PubMed, Systematic Review, Meta-analysis, and Trial Sequential Analysis of Randomised Controlled Trials Comparing Balloon Expandable with Self Expanding Stents for the Treatment of Iliac Artery Occlusive Disease
  3. Pediatric Cardiology — Comparative Efficacy of Drug-Eluting Balloons and Standard Balloon Angioplasty in Treating Peripheral Pulmonary Artery Stenosis in Pediatric Patients
  4. Clinical Research in Cardiology — Evaluation of the Antirestenotic Effectiveness of Two Paclitaxel-Coated Drug-Eluting Balloons for Managing In-Stent Restenosis
  5. Clinical Research in Cardiology — Outcomes Over Time Following Covered Balloon-Expandable Stent Placement for Vascular Injury Management in Patients Undergoing Transfemoral Transcatheter Aortic Valve Implantation: Insights from the BE-SAFE Registry
  6. Identifying Risk Factors for In-Stent Stenosis Following Flow-Diverter Placement in Patients with Intracranial Aneurysms: Insights from a Single-Center Study of 161 Cases
  7. 2024 ACC/AHA/Multisociety Guideline for Lower Extremity PAD: Key Points - American College of Cardiology
  8. Systematic Review, Meta-analysis, and Trial Sequential Analysis of Randomised Controlled Trials Comparing Balloon Expandable with Self Expanding Stents for the Treatment of Iliac Artery Occlusive Disease - PubMed

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