Diffuse large B-cell lymphoma presenting as a scalp tumor with skull destruction and neurological symptoms: a case report - Report - MDSpire

Diffuse large B-cell lymphoma presenting as a scalp tumor with skull destruction and neurological symptoms: a case report

  • By

  • Ayaka Yasuda

  • Natsuko Saito-Sasaki

  • Hirofumi Kawamoto

  • Yu Sawada

  • May 29, 2026

Share

Clinical Report: Diffuse Large B-Cell Lymphoma Manifesting as a Scalp Lesion

Overview

{'treatment_details': 'Include specifics on CNS-directed therapy.'}

Background

{'context': 'Expand on the clinical implications of cutaneous manifestations.'}

Data Highlights

{'additional_parameters': 'Include performance status or IPI score.'}

Key Findings

{'RANKL_significance': 'Explain its relevance to treatment outcomes.'}

Clinical Implications

{'urgency': 'Highlight the need for prompt diagnosis and treatment.'}

Conclusion

{'recognition': 'Stress the importance of identifying rare DLBCL presentations.'}

Related Resources & Content

  1. Frontiers in Oncology, 2026 -- Case Report: Leptomeningeal involvement in chronic lymphocytic leukemia patients with central nervous system infection
  2. The ASCO Post, 2015 -- Answers: Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System
  3. Understanding Delays in Diagnosis and Treatment of Primary Central Nervous System Lymphoma, 2024 -- Insights for Neurosurgeons
  4. Frontiers in Oncology, 2026 -- Case Report: Extranodal marginal zone B-cell lymphoma in the lateral ventricle
  5. Diffuse large B-cell lymphoma of the skull vault - PubMed, 2023
  6. Five-Year Outcomes of the POLARIX Study, 2026 -- Comparing Pola-R-CHP and R-CHOP in Patients With Diffuse Large B-Cell Lymphoma
  7. Incidence and characterization of secondary CNS lymphoma in 1972 patients with DLBCL, 2025 -- Blood Advances
  8. Diffuse large B-cell lymphoma of the skull vault - PubMed
  9. Five-Year Outcomes of the POLARIX Study
  10. Incidence and characterization of secondary CNS lymphoma in 1972 patients with DLBCL: a Danish nationwide cohort study | Blood Advances | American Society of Hematology

Original Source(s)

Diffuse large B-cell lymphoma presenting as a scalp tumor with skull destruction and neurological symptoms: a case report

  • by Ayaka Yasuda, Natsuko Saito-Sasaki, Hirofumi Kawamoto, Yu Sawada

  • May 29, 2026

Related Content

Why We Made a Mobile Digital Pathology Lab

Todd R. Minnigh and his team created ScanVan to address a problem with rare cancer diagnosis that had a particularly personal significance

Could One Test Replace Multiple Leukemia Assays?

Researchers assess whether long-read transcriptome sequencing can streamline B-ALL diagnostics

  • May 29, 2026

  • 3 min
Preclinical Study in Mice Addresses a Question: Should RAS Inhibitors Be Given Preemptively?

With recent data that RAS inhibition can improve survival in metastatic pancreatic cancer, the optimization of these agents has become a research priority. Minh Than, MD, PhD, a clinical and research ...