Recurrent dysplasia epiphysealis hemimelica: a case report and review of the literature

By
Yakun Zhou
Dongfeng Chen
Ruotong Li
Yanchen Liang
Xiuming Miao
May 25, 2026

Frontiers In Medicine

Overview

This report details a case of recurrent Dysplasia Epiphysealis Hemimelica (DEH) in a 9-year-old female, highlighting the challenges of diagnosis and management. The recurrence occurred three months post-surgery, characterized by increased pain and stiffness, emphasizing the need for careful postoperative monitoring.

Background

Dysplasia Epiphysealis Hemimelica (DEH) is a rare disorder of epiphyseal development, primarily affecting children and often leading to osteochondral overgrowth. Its low incidence and potential for misdiagnosis necessitate heightened clinical awareness. Understanding the recurrence patterns and management strategies is crucial for improving patient outcomes.

Data Highlights

No numerical data or trial data available in the article.

Key Findings

The patient experienced recurrence of DEH three months after initial surgical excision.
Histopathological analysis revealed immature fibrocartilaginous tissue and a foreign-body granulomatous reaction.
Recurrence is linked to incomplete surgical excision and the patient's age.
Improved recognition of DEH's clinical manifestations is essential for timely diagnosis.
Postoperative follow-up protocols are recommended to mitigate recurrence risks.

Clinical Implications

Clinicians should maintain a high index of suspicion for DEH in pediatric patients presenting with atypical bone lesions. A thorough postoperative follow-up is essential to monitor for recurrence, particularly in cases with incomplete excision.

Conclusion

This case underscores the importance of recognizing DEH and implementing effective follow-up strategies to manage potential recurrences. Enhanced awareness and tailored management can improve outcomes for affected patients.