Distribution of HPV Genotypes and Epidemiological Insights in Northern Iran - Report - MDSpire

Distribution of HPV Genotypes and Epidemiological Insights in Northern Iran

  • By

  • Hadi Razavi Nikoo

  • Sedigheh Damavandi Kamali

  • Sahar Lashkari

  • Raheleh Rezaie

  • Alijan Tabarraei

  • Hojjat Allah Yami

  • Hamid Reza Joshaghani

  • Fatemeh Mehravar

  • Malihe Azadehrah

  • February 14, 2026

  • 0 min

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Clinical Report: Distribution of HPV Genotypes in Northern Iran

Overview

This study investigates the prevalence and genotype distribution of HPV in Golestan province, Northern Iran, highlighting significant findings related to high-risk HPV types. The data underscores the urgent need for enhanced HPV vaccination and screening efforts in the region.

Background

HPV infection is a major public health issue due to its link to various cancers, especially cervical cancer. With cervical cancer being a leading cause of cancer mortality among women, understanding local HPV epidemiology is crucial for effective prevention strategies. The study addresses the gap in HPV data from Northern Iran, which is essential for guiding public health initiatives.

Data Highlights

ParameterValue
Participants1,004
Women996
Men8
HPV Testing MethodHybrid Capture II

Key Findings

  • The study included 1,004 participants, predominantly women (996).
  • HPV DNA testing was performed using the Hybrid Capture II system.
  • High-risk HPV types were prevalent, particularly HPV16 and HPV18.
  • Low HPV vaccination rates were noted, indicating a need for increased awareness and accessibility.
  • Regional variability in HPV genotype distribution was observed, emphasizing the importance of localized data.

Clinical Implications

Healthcare providers should prioritize HPV vaccination and screening in Northern Iran to reduce cervical cancer incidence. Understanding the local genotype distribution can inform targeted public health strategies and educational campaigns.

Conclusion

The findings highlight the critical need for improved HPV vaccination and screening efforts in Northern Iran, informed by local epidemiological data. Continued research is essential to monitor HPV trends and guide public health interventions.

References

  1. American Journal of Epidemiology, 2023 -- Genotype Patterns of High-Risk Human Papillomavirus and Cervical Cytology Abnormalities in Women from Tripura, Northeastern India: A Hospital-Based Analysis
  2. Infection, 2023 -- The Incidence of Human Papillomavirus in Ocular Surface Squamous Neoplasia Among HIV Positive and Negative Individuals in a South African Cohort
  3. The Journal of Infectious Diseases, 2023 -- Population-Based Age-Period-Cohort Analysis of Declining Human Papillomavirus Prevalence
  4. Self-Collected Vaginal Specimens for HPV Testing: Recommendations From the Enduring Consensus Cervical Cancer Screening and Management Guidelines Committee - PubMed
  5. The Journal of Infectious Diseases — Evaluation of Concurrent Human Papillomavirus Infections with 9-Valent Vaccine Types in Anogenital Regions Among Young Males
  6. Epidemiology and genotype distribution of human papillomavirus (HPV) in Northern Iran
  7. Self-Collected Vaginal Specimens for HPV Testing: Recommendations From the Enduring Consensus Cervical Cancer Screening and Management Guidelines Committee - PubMed
  8. Invasive cervical cancer incidence following bivalent human papillomavirus vaccination: a population-based observational study of age at immunization, dose, and deprivation | JNCI: Journal of the National Cancer Institute | Oxford Academic

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