Assessment of Measles Immunity in Türkiye's Central Black Sea Region - Report - MDSpire

Assessment of Measles Immunity in Türkiye's Central Black Sea Region

  • By

  • Hacer Ozlem Kalayci

  • Yunus Emre Ibik

  • Mustafa Kerem Calgin

  • February 9, 2026

  • 0 min

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Clinical Report: Assessment of Measles Immunity in Türkiye's Central Black Sea Region

Overview

This study evaluates measles immunity levels in the Central Black Sea Region of Türkiye, revealing an overall seropositivity of 70.7% among 5,252 individuals tested. The findings highlight significant age-related differences in immunity, emphasizing the need for targeted vaccination strategies.

Background

Measles remains a major public health concern due to its high transmissibility and potential for severe complications. Despite effective vaccination programs, global vaccine hesitancy and disruptions caused by the COVID-19 pandemic have led to increased measles cases. Continuous monitoring of population immunity is essential for preventing outbreaks and ensuring effective immunization strategies.

Data Highlights

This study analyzed serological data from 5,252 patients, revealing an overall measles IgG seropositivity of 70.7%.

Key Findings

  • Overall measles IgG seropositivity in the study population was 70.7%.
  • Participants were categorized into three age groups: 4–30 years, 31–40 years, and ≥ 41 years.
  • The mean age of participants was 31.8 years, with a median age of 29 years.
  • Historical vaccination policies have resulted in heterogeneous immunity profiles across different birth cohorts.
  • Monitoring of immunity levels is crucial for effective measles elimination strategies.

Clinical Implications

Healthcare providers should be aware of the varying levels of measles immunity across different age groups and consider targeted vaccination efforts to address gaps. Continuous serological assessments can inform public health strategies to prevent future outbreaks.

Conclusion

Reiterate the importance of continuous monitoring and provide a call to action for public health authorities.

References

  1. Open Forum Infectious Diseases, 2021 -- Evaluation of Measles Immunity Levels in Hunan, China: A Serological Study
  2. American Journal of Epidemiology, 2021 -- Analyzing Measles Immunity Patterns Amid Fluctuating Measles Outbreaks in Madagascar
  3. Infection, 2018 -- Prevalence of Immunoglobulin G Antibodies Against Measles and Rubella Among Individuals Aged 1 to 30 in England in 2018: Insights for Predicting Future Outbreaks
  4. WHO, 2026 -- Measles cases dropped in Europe and Central Asia in 2025 compared to the previous year, but the risk of outbreaks remains
  5. Open Forum Infectious Diseases — Analysis of Rubella Virus Epidemiology in a Conflict-affected Region: A Retrospective Review of 11 Years of Case Data from South Sudan
  6. ECDC’s 2024 Measles Annual Epidemiological Report
  7. Measles cases dropped in Europe and Central Asia in 2025 compared to the previous year, but the risk of outbreaks remains – UNICEF and WHO

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