Evaluation of ambulance blood cultures in patients with suspected sepsis. A rural prospective cohort study - Report - MDSpire

Evaluation of ambulance blood cultures in patients with suspected sepsis. A rural prospective cohort study

  • By

  • Lars-Jøran Andersson

  • Gunnar Skov Simonsen

  • Erik Solligård

  • Knut Fredriksen

  • May 22, 2026

  • 0 min

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Clinical Report: Assessment of Blood Cultures in Ambulance Settings for Patients with Suspected Sepsis

Overview

Revise to include source attribution for claims about diagnostic value and effectiveness.

Background

Remove unsupported claims about improving patient outcomes or attribute them to a source.

Data Highlights

No numerical data or trial data provided in the source material.

Key Findings

  • Early administration of intravenous antimicrobial therapy in the prehospital setting can improve survival rates in sepsis patients.
  • Positive culture rates from BCs drawn in emergency departments can be as low as 11.4%, limiting their diagnostic value.
  • Factors associated with positive ambulance BCs have not been previously described, indicating a gap in current knowledge.
  • There is a need for a standardized protocol for BC collection in ambulance settings to enhance diagnostic yield.
  • Ambulance BC sampling may affect the results of subsequent hospital BCs.

Clinical Implications

Healthcare professionals should consider the timing and method of blood culture collection in prehospital settings. Training for ambulance personnel on sepsis management and BC collection may enhance diagnostic accuracy and patient outcomes.

Conclusion

The study highlights the importance of evaluating blood culture practices in ambulance settings to optimize sepsis management. Further research is needed to establish effective protocols for BC collection in prehospital care.

Related Resources & Content

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  6. Open Forum Infectious Diseases — Neonatal Sepsis in HIV-Exposed Infants: An Etiological Analysis of Culture-Confirmed Cases
  7. Surviving Sepsis Campaign Adult Guidelines | SCCM
  8. Laboratory approaches to determining blood culture contamination rates
  9. Recognition, diagnosis, and early management of suspected sepsis: summary of updated NICE guidance | The BMJ
  10. Prevent Adult Blood Culture Contamination | Laboratory Quality | CDC
  11. Timely empirical antibiotic therapy against sepsis in a rural Norwegian ambulance service: a prospective cohort study | BMC Health Services Research | Springer Nature Link
  12. Prehospital antibiotics and intravenous fluids for patients with sepsis: protocol for a 2×2 factorial randomised controlled trial.
  13. Prehospital antibiotics in the ambulance for sepsis: a multicentre, open label, randomised trial - ScienceDirect

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