Relationships between anxiety–depression, perceived social support, and in-hospital outcomes among patients with acute myocardial infarction - Report - MDSpire

Relationships between anxiety–depression, perceived social support, and in-hospital outcomes among patients with acute myocardial infarction

  • By

  • Yuemei Zhu

  • Xiao Zhu

  • Yingying Zhou

  • June 16, 2026

  • 0 min

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Connections between anxiety-depression, perceived social support, and hospital outcomes in AMI patients

Overview

This study investigates the associations between early anxiety-depression symptoms, perceived social support, and in-hospital outcomes in acute myocardial infarction (AMI) patients. Findings indicate that higher anxiety-depression symptoms correlate with increased complication risk and prolonged hospital stays, while greater perceived social support is linked to better outcomes.

Background

Acute myocardial infarction (AMI) is a critical condition with high mortality and morbidity rates. Psychological factors, such as anxiety and depression, are increasingly recognized as influential in the recovery and outcomes of AMI patients. Understanding these associations can enhance patient care and resource utilization during hospitalization.

Data Highlights

ParameterFindings
Patients with anxiety-depression symptoms (HADS ≥11)44.0%
Patients developing complications27.3%
Association of higher HADS scoresIncreased complication risk, prolonged stay, poorer sleep quality (all P < 0.05)
Association of higher PSSS scoresReduced complication risk, shorter stay, better sleep quality (all P < 0.05)

Key Findings

  • 44.0% of AMI patients exhibited clinically significant anxiety-depression symptoms.
  • 27.3% of patients experienced at least one complication during hospitalization.
  • Higher HADS scores were linked to increased complication risk and prolonged hospital stays.
  • Higher PSSS scores correlated with reduced complication risk and improved sleep quality.
  • Psychosocial risk stratification showed a significant gradient across all outcomes.

Clinical Implications

Routine psychosocial screening for anxiety and depression in AMI patients may help identify those at higher risk for complications. Enhanced social support could be integrated into care plans to improve patient outcomes during hospitalization.

Conclusion

The study highlights the importance of early assessment of psychological factors and social support in AMI patients, suggesting that these elements are critical for improving in-hospital outcomes.

Related Resources & Content

  1. European Journal of Preventive Cardiology, 2023 -- Anxiety and depression and secondary prevention of coronary heart disease in 14 countries across six WHO regions: the INTERASPIRE study
  2. BMC Psychiatry, 2023 -- The effectiveness of a multi-dimensional intervention model combining cognitive behavioral therapy and social support in hospitalized depressed patients
  3. Frontiers in Cardiovascular Medicine, 2026 -- Network analysis identifies core fear symptoms as screening clues for post-PCI rehabilitation in patients with acute myocardial infarction
  4. 2025 Guideline for Acute Coronary Syndromes - Professional Heart Daily | American Heart Association
  5. Enhancing Recovery in Coronary Heart Disease - American College of Cardiology
  6. conexiant — What's Heart Disease Got to Do With It?
  7. Prevalence of Depression, Anxiety and Post-Traumatic Stress Disorder (PTSD) After Acute Myocardial Infarction: A Systematic Review and Meta-Analysis
  8. 2025 Guideline for Acute Coronary Syndromes - Professional Heart Daily | American Heart Association
  9. Enhancing Recovery in Coronary Heart Disease - American College of Cardiology

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