Clinical Report: ALK-Positive Spitz Nevus on the Nasal Dorsum in a Pediatric Patient

Background

Spitz nevus is a benign melanocytic lesion commonly found in children and adolescents, often presenting as solitary lesions. Understanding the clinical and pathological features of Spitz nevi is crucial for appropriate management and follow-up.

Data Highlights

No numerical or trial data presented in the article.

Key Findings

• The patient presented with a 2.5 cm × 1.5 cm asymptomatic erythematous patch on the nasal dorsum.
• Histopathological examination revealed spindle-shaped cell proliferation without nuclear fission.
• Immunohistochemical analysis showed positive markers including S100, SOX10, and ALK.
• Complete surgical excision was performed, and postoperative diagnosis confirmed the preoperative findings.
• No recurrence was observed after more than one year of follow-up.

Clinical Implications

Surgical excision remains the recommended treatment for larger lesions or those with atypical characteristics.

Conclusion

The case highlights the recognition of ALK-positive Spitz nevus in pediatric patients.

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