Comparison of clinical efficacy between endoscope-assisted oblique lumbar interbody fusion and posterior lumbar interbody fusion in the treatment of lumbar degenerative diseases - Report - MDSpire

Comparison of clinical efficacy between endoscope-assisted oblique lumbar interbody fusion and posterior lumbar interbody fusion in the treatment of lumbar degenerative diseases

  • By

  • Haoran Han

  • Can Cao

  • Zekai Sun

  • Wenyi Li

  • May 28, 2026

  • 0 min

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Clinical Report: Endoscope-Assisted OLIF vs. PLIF for Lumbar Disorders

Overview

This study compares the clinical outcomes of endoscope-assisted oblique lumbar interbody fusion (Endo-OLIF) and posterior lumbar interbody fusion (PLIF) in treating lumbar degenerative diseases. Endo-OLIF demonstrated advantages in operative time, blood loss, and early post-operative recovery, while both techniques showed similar long-term functional outcomes.

Background

Lumbar degenerative diseases are prevalent conditions that significantly impact the quality of life, particularly in middle-aged and elderly populations. Traditional PLIF has been the gold standard for surgical intervention but is associated with longer recovery times and higher complication rates. The emergence of minimally invasive techniques like Endo-OLIF aims to improve surgical outcomes and patient recovery.

Data Highlights

OutcomeEndo-OLIFPLIF
Operative TimeShorterLonger
Intra-operative Blood LossLessMore
Post-operative Drainage VolumeLowerHigher
Length of Hospital StayShorterLonger
Early Post-operative VAS ScoresLowerHigher
Early Post-operative ODI ScoresLowerHigher
Fusion RateSimilarSimilar
Cage Subsidence RateSimilarSimilar
Complication RateSimilarSimilar

Key Findings

  • The Endo-OLIF group had significantly shorter operative times compared to the PLIF group.
  • Intra-operative blood loss and post-operative drainage volumes were lower in the Endo-OLIF group.
  • Early post-operative VAS and ODI scores were significantly better in the Endo-OLIF group.
  • Both techniques had similar fusion and subsidence rates.
  • Restoration of disc height and lumbar lordosis was significantly better in the Endo-OLIF group.
  • No significant differences in complication rates were observed between the two groups.

Clinical Implications

The findings suggest that Endo-OLIF may provide a more favorable early recovery profile and better restoration of spinal alignment compared to PLIF. Surgeons may consider Endo-OLIF as a viable option for patients with lumbar degenerative diseases, particularly those who may benefit from a minimally invasive approach.

Conclusion

Endo-OLIF offers significant advantages in terms of operative efficiency and early recovery while maintaining comparable long-term outcomes to PLIF. Further studies are warranted to validate these findings and explore the long-term implications of this technique.

Related Resources & Content

  1. Author(s)/Org, Source, Year -- Title
  2. Comparative Effectiveness of Oblique Lumbar Interbody Fusion and Transforaminal Lumbar Interbody Fusion for Lumbar Degenerative Conditions: A Systematic Review and Meta-Analysis
  3. Comparative analysis of single vs. double cage insertion in unilateral biportal endoscopic lumbar interbody fusion: clinical and radiological outcomes
  4. Outcomes of Lumbar Spinal Fusion Surgery for Degenerative Spondylolisthesis: Results from a Three-Year Follow-Up Study
  5. Decompression alone or decompression with fusion for lumbar spinal stenosis: five-year clinical results from a randomized clinical trial
  6. Stabilization of the Lumbar Spine Using PEEK Rods and TLIF with Titanium Rods in Patients Over 70 with Single-Level Degenerative Disease
  7. Advances in endoscopic lumbar spine surgery: a comprehensive review
  8. Decompression alone or decompression with fusion for lumbar spinal stenosis: five-year clinical results from a randomized clinical trial - PubMed
  9. Frontiers | Comparison of Clinical Efficacy Between Endoscope-Assisted Oblique Lumbar Interbody Fusion and Posterior Lumbar Interbody Fusion in the Treatment of Lumbar Degenerative Diseases

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