One patient with synchronous multiple primary colon cancers which is easy to miss: a case report - Report - MDSpire
Coming Soon: Introducing MDSpire News. Learn more
Conexiant’s news site is now MDSpire News. Learn more

A Case Report of Synchronous Multiple Primary Colon Cancers: A Rare Presentation Often Overlooked

  • By

  • Xinmin Bao

  • Haoru Liu

  • Ming Wu

  • Xianwei Liu

  • September 15, 2026

Share

Clinical Report: A Case of Synchronous Multiple Primary Colon Cancers

Background

Synchronous multiple primary colon cancer (MPCC) is an uncommon condition characterized by the presence of two or more primary colon cancers diagnosed within a short timeframe. The challenge of diagnosing MPCC is compounded by the frequent occurrence of endoscopic obstruction in advanced cases, which can hinder complete evaluation.

Data Highlights

No numerical data or trial data available in the source material.

Key Findings

  • A 70-year-old woman presented with sigmoid colon cancer and endoscopic obstruction.
  • Enhanced abdominal CT revealed bowel-wall thickening and two lesions in the transverse colon.
  • Intraoperative findings included marked thickening in multiple colon segments and enlarged lymph nodes.
  • Pathological examination confirmed adenocarcinoma in the sigmoid, transverse, and ascending colon.
  • Intraoperative exploration revealed multiple synchronous cancers.

Clinical Implications

Clinicians should consider the potential for multiple primary cancers in patients with obstructive colon cancer.

Conclusion

This case highlights the complexities of diagnosing synchronous multiple primary colon cancers.

Related Resources & Content

  1. Frontiers in Oncology, 2026 -- A case of synchronous double primary combined hepatocellular-cholangiocarcinoma complicated with gallbladder adenocarcinoma: a rare case report
  2. Frontiers in Surgery, 2026 -- Concurrent Multiple Primary Colorectal Cancers with Divergent RAS Status in Primary Tumors: A Case Study of an Elderly Individual
  3. Frontiers in Surgery, 2026 -- Concurrent Adenocarcinoma of the Right Colon and Sigmoid Endometriosis Presenting as a Potential Second Primary Tumor: A Case Study
  4. Frontiers in Oncology — Synchronous primary breast invasive carcinoma and breast metastasis from high-grade serous ovarian carcinoma: a case report and literature review
  5. Impact of rurality on patients with synchronous colorectal cancers.
  6. American Society for Gastrointestinal Endoscopy guideline on endoscopic management of benign and malignant colonic strictures.
  7. Solid Tumor Rules 2026.1 Update
  8. ACR Appropriateness Criteria® Colorectal Cancer Screening: 2024 Update - PubMed
  9. ASGE | New ASGE Guideline on Endoscopic Management of Benign and Malignant Colonic Strictures
  10. Colonic Stenting as a Bridge to Surgery Versus Emergency Resection in Left-Sided Malignant Large Bowel Obstruction: A Systematic Review - PubMed
  11. Laparoscopic-assisted vs open surgery for synchronous colorectal cancer: a retrospective cohort study of short-term and long-term outcomes | BMC Gastroenterology | Springer Nature Link
  12. Mismatch Repair and Microsatellite Instability Testing for Immune Checkpoint Inhibitor Therapy: ASCO Endorsement of College of American Pathologists Guideline

Original Source(s)

Related Content