Non-invasive electrical stimulation for sleep disturbances in adults: protocol for an evidence−mapping umbrella review of systematic reviews and meta−analyses with subgroup analysis by intervention type and population - Report - MDSpire

Non-invasive electrical stimulation for sleep disturbances in adults: protocol for an evidence−mapping umbrella review of systematic reviews and meta−analyses with subgroup analysis by intervention type and population

  • By

  • Jingyi Zhu

  • Yitong Lin

  • Yuanyuan Chen

  • Baixiao Zhao

  • May 28, 2026

  • 0 min

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Protocol for an Umbrella Review of Non-Invasive Electrical Stimulation for Sleep Disorders

Overview

This umbrella review aims to synthesize evidence from systematic reviews and meta-analyses on non-invasive electrical stimulation (NIES) for adult sleep disorders. It will assess methodological quality, quantify overlap, and describe evidence patterns across various modalities and populations.

Background

Sleep disturbances affect a significant portion of the adult population, leading to various health issues and reduced quality of life. Conventional treatments often have limitations, prompting the exploration of non-invasive electrical stimulation techniques as potential alternatives. This review seeks to provide a comprehensive overview of existing evidence regarding NIES interventions for sleep improvement.

Data Highlights

No numerical data or trial results are provided in the source material.

Key Findings

  • Sleep disturbances affect 10%–30% of adults globally.
  • Non-invasive electrical stimulation techniques include transcranial electrical stimulation and transcutaneous electrical nerve stimulation.
  • Existing systematic reviews on NIES show considerable variability in methodological quality and populations.
  • This umbrella review will follow JBI guidelines and assess the quality of included reviews using AMSTAR 2.
  • The primary outcome of interest is subjective sleep quality, with total sleep time as a secondary outcome.

Clinical Implications

The findings from this umbrella review may help identify effective NIES modalities for sleep disorders and highlight areas needing further investigation. Clinicians should remain aware of the evolving evidence landscape regarding non-pharmacological interventions for sleep disturbances.

Conclusion

This umbrella review aims to provide a high-level synthesis of evidence on non-invasive electrical stimulation for sleep disorders, addressing gaps in the current literature. It will contribute to understanding the efficacy and applicability of these interventions.

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