Attention-deficit/hyperactivity disorder and chronic pain: a scoping review of epidemiology, clinical phenotypes, mechanisms, and treatment - Report - MDSpire
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Attention-deficit/hyperactivity disorder and chronic pain: a scoping review of epidemiology, clinical phenotypes, mechanisms, and treatment
Clinical Report: Exploring the Relationship Between ADHD and Chronic Pain
Overview
This scoping review synthesizes evidence on the association between attention-deficit/hyperactivity disorder (ADHD) and chronic pain, highlighting significant comorbidities and potential neurobiological mechanisms.
Background
Chronic pain is a significant public health issue, impacting quality of life and imposing a socioeconomic burden. ADHD, a neurodevelopmental disorder, is increasingly recognized as a potential comorbidity in chronic pain populations.
Data Highlights
Fifty studies were included in the review, revealing significant associations between ADHD and chronic pain across various conditions, including observational studies and case reports.
Key Findings
Epidemiological studies consistently report a significant association between ADHD symptoms and chronic pain.
Comorbid ADHD is observed in widespread pain syndromes like fibromyalgia and specific conditions such as chronic low back pain and migraines.
Proposed mechanisms include dopaminergic and noradrenergic dysfunction affecting pain modulation.
Clinical Implications
Recognizing ADHD traits may inform individualized treatment approaches.
Conclusion
The review highlights the association between ADHD and chronic pain comorbidity.
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