SEE Program Strengthens Adherence - Report - MDSpire

SEE Program Strengthens Adherence

  • April 3, 2026

  • 3 min

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Clinical Report: SEE Program Strengthens Adherence

Overview

The SEE program, a motivational interviewing-based coaching intervention, significantly improved medication adherence and reduced glaucoma-related distress compared to standard education. This randomized clinical trial involved 235 adults with glaucoma and demonstrated a marked increase in adherence rates and a decrease in distress scores over six months.

Background

Medication adherence is a critical aspect of managing chronic conditions like glaucoma, where poor adherence can lead to adverse outcomes. The SEE trial addresses this issue by implementing a structured coaching program that combines personalized education and motivational interviewing. Understanding effective adherence strategies is essential for improving patient outcomes and reducing healthcare costs.

Data Highlights

GroupAdherence Rate (%)Distress Score Change
SEE Intervention77.6Improved
Control Group58.0Moderate

Key Findings

  • The SEE program improved electronically monitored adherence from 63.9% at baseline to 77.6% at six months.
  • 54.9% of SEE participants achieved at least 80% adherence, compared to 23.7% in the control group.
  • Participants in the SEE group experienced a significant reduction in glaucoma-related distress scores.
  • The intervention's effects were consistent across various sensitivity analyses.
  • The SEE program utilized a web-based system for personalized education and structured coaching.

Clinical Implications

Healthcare providers should consider implementing structured, motivational interviewing-based coaching programs to enhance medication adherence among glaucoma patients. Such interventions can lead to improved patient outcomes and reduced distress, ultimately benefiting both patients and the healthcare system.

Conclusion

The SEE program demonstrates that personalized coaching can effectively improve medication adherence and reduce distress in glaucoma patients. Future research should explore the long-term impacts of such interventions on clinical outcomes.

References

  1. JAMA Ophthalmology, 2023 -- SEE Program Strengthens Adherence
  2. optometric management — Utilizing Staff for Patient Adherence
  3. Ophthalmology Management — Medication Adherence Interventions That Work
  4. The ASCO Post — UC Davis Comprehensive Cancer Center Tailors Pilot Program to Help Patients Adhere to Oral Chemotherapy
  5. Drugs - Real World Outcomes — Pharmacist-Led Strategies to Enhance Adherence to Specialty Medications: Protocol for a Randomized Controlled Trial
  6. Utilizing Staff for Patient Adherence
  7. Medication Adherence Interventions That Work
  8. UC Davis Comprehensive Cancer Center Tailors Pilot Program to Help Patients Adhere to Oral Chemotherapy
  9. Advancing glaucoma care: What's new in the 6th edition of the European Glaucoma Society guidelines
  10. Selective laser trabeculoplasty versus eye drops for first-line treatment of ocular hypertension and glaucoma (LiGHT): a multicentre randomised controlled trial - PubMed
  11. Interventions for Glaucoma Medication Adherence Improvement: A Network Meta-analysis of Randomized Controlled Trials - PubMed

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