Recent progress in postoperative nausea and vomiting after thyroidectomy - Report - MDSpire

Recent progress in postoperative nausea and vomiting after thyroidectomy

  • By

  • Qihao Zhao

  • Fuling Song

  • Meimei Cui

  • Haoping Jia

  • Rongzhan Fu

  • Guanghan Wu

  • Dongsheng Zhou

  • July 8, 2026

  • 0 min

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Clinical Report: Advancements in Managing Postoperative Nausea and Vomiting Following Thyroid Surgery

Overview

Postoperative nausea and vomiting (PONV) is a significant complication following thyroidectomy. Effective management strategies, including multimodal prophylaxis and individualized risk assessments, are essential to mitigate PONV.

Background

PONV is a common complication after thyroid surgery, leading to increased risks of serious postoperative issues such as hematoma formation and airway compromise. Understanding the specific risk factors associated with thyroidectomy can help tailor prevention strategies.

Data Highlights

No numerical data provided in the source material.

Key Findings

  • PONV occurs in approximately 30%-40% of general surgical patients, rising to 60%-84% in thyroidectomy patients without prophylaxis, according to recent studies.
  • Risk factors for PONV include female sex, non-smoking status, and a history of motion sickness or prior PONV.
  • Thyroidectomy-specific factors such as neck positioning and vagal nerve stimulation contribute to increased PONV risk.
  • Multimodal prophylactic strategies, including total intravenous anesthesia (TIVA) and the use of 5-HT3 receptor antagonists, are recommended to reduce PONV.
  • Individualized antiemetic strategies based on comprehensive risk assessments are essential for effective management of PONV.

Clinical Implications

Anesthesiologists and surgeons should consider individualized risk assessments to identify patients at high risk for PONV.

Conclusion

Effective management of PONV in thyroidectomy patients requires a comprehensive understanding of risk factors and the application of tailored prophylactic strategies.

Related Resources & Content

  1. Surgical Endoscopy, 2025 -- Utilization of Intraoperative Neuromonitoring Decreases Risk of Vocal Cord Damage During Open Surgery for Thyroid Cancer: Findings from a Randomized Controlled Study
  2. Updates in Surgery, 2025 -- Intraoperative Signal Recovery Correlates with Normal Postoperative Vocal Cord Function in Patients Experiencing Signal Loss During Surgery
  3. Combined Use of Bilateral Superficial Cervical Plexus Block and General Anesthesia in Thyroid Surgery, 2010
  4. Efficacy and safety of perioperative dexmedetomidine infusion in thyroid surgery: a systematic review and meta-analysis of randomized controlled trials, 2026
  5. Impact of oliceridine versus sufentanil on postoperative nausea and vomiting in patients undergoing thyroid surgery: a prospective, double-blind, randomized controlled trial, PMC
  6. Updates in Surgery — Assessing the Risk of Surgical Site Infections in Transoral Thyroid Surgery via the Vestibular Approach
  7. 2026 Fifth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting
  8. Efficacy and safety of perioperative dexmedetomidine infusion in thyroid surgery: a systematic review and meta-analysis of randomized controlled trials | BMC Anesthesiology | Springer Nature Link
  9. Impact of oliceridine versus sufentanil on postoperative nausea and vomiting in patients undergoing thyroid surgery: a prospective, double-blind, randomized controlled trial - PMC

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