A retrospective study comparing holmium Laser enucleation vs. transurethral resection for the treatment of benign prostatic hyperplasia - Report - MDSpire
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A retrospective study comparing holmium Laser enucleation vs. transurethral resection for the treatment of benign prostatic hyperplasia
Clinical Report: Holmium Laser Enucleation vs. Transurethral Resection for BPH
Overview
This study compares the perioperative outcomes and short-term efficacy of holmium laser enucleation of the prostate (HoLEP) versus transurethral resection of the prostate (TURP) in patients with benign prostatic hyperplasia (BPH).
Background
Benign prostatic hyperplasia (BPH) is a prevalent condition in aging men, leading to significant lower urinary tract symptoms that affect quality of life. Surgical intervention is often necessary when medical management fails, with TURP traditionally being the gold standard. However, TURP has limitations, prompting interest in alternative techniques like HoLEP.
Data Highlights
Parameter
HoLEP
TURP
P-value
Operation Time (min)
58.26 ± 20.11
84.17 ± 36.80
< 0.001
Catheterization Time (days)
5.37 ± 1.45
6.27 ± 1.47
< 0.001
Hospital Stay (days)
7.33 ± 3.12
13.61 ± 4.14
< 0.001
Urinary Tract Irritation (%)
22.62
42.86
< 0.05
Erectile Dysfunction (%)
16.67
29.76
< 0.05
Key Findings
HoLEP resulted in a significantly shorter operation time compared to TURP (58.26 min vs. 84.17 min, P < 0.001).
Patients undergoing HoLEP had a shorter catheterization time (5.37 days vs. 6.27 days, P < 0.001).
The hospital stay was significantly reduced for HoLEP patients (7.33 days vs. 13.61 days, P < 0.001).
HoLEP showed lower rates of urinary tract irritation (22.62% vs. 42.86%, P < 0.05).
Erectile dysfunction rates were lower in the HoLEP group (16.67% vs. 29.76%, P < 0.05).
Clinical Implications
The findings indicate differences in perioperative outcomes between HoLEP and TURP.
Conclusion
HoLEP offers advantages in perioperative outcomes compared to TURP.
Postoperative rates of complex regional pain syndrome type 1 and pain and functional outcomes may improve among patients receiving prophylactic mecobalamin following foot and ankle surgery.
