Regional intra-arterial infusion chemotherapy combined with deep hyperthermia and targeted therapy followed by radiotherapy for recurrence with intestinal obstruction after radical resection of rectal cancer in an elderly patient: a case report of individualized treatment - Report - MDSpire
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Regional intra-arterial infusion chemotherapy combined with deep hyperthermia and targeted therapy followed by radiotherapy for recurrence with intestinal obstruction after radical resection of rectal cancer in an elderly patient: a case report of individualized treatment
Clinical Report: Tailored Treatment for Local Recurrence of Rectal Cancer
Overview
This case report details the management of local recurrence of rectal cancer with intestinal obstruction in an elderly patient. A treatment strategy involving regional intra-arterial chemotherapy, deep hyperthermia, targeted therapy, and radiotherapy was implemented.
Background
Local recurrence rates of rectal cancer can be significantly higher in elderly patients, often complicated by intestinal obstruction. This case highlights the management of complex recurrences.
Data Highlights
No numerical data or trial data presented in the article.
Key Findings
The local recurrence rate after radical resection of rectal cancer is 5%-20%, increasing to 20%-35% in elderly patients without adjuvant therapy.
Intestinal obstruction is a common complication of recurrence, with a median survival of only 6-7 months.
The patient achieved complete remission following a treatment regimen of regional intra-arterial chemotherapy, deep hyperthermia, and bevacizumab.
No severe adverse events were reported during the treatment process.
Follow-up indicated favorable quality of life and preserved performance status for the patient.
Clinical Implications
Individualized treatment strategies for elderly patients with recurrent rectal cancer are important. Multidisciplinary approaches can be beneficial.
Conclusion
The management of this case illustrates the use of multimodal treatment strategies in achieving remission for elderly patients with complex rectal cancer recurrences.
