Long-term cardiovascular impact of COVID-19 among hospitalised and non-hospitalised populations: a narrative synthesis review - Report - MDSpire

Long-term cardiovascular impact of COVID-19 among hospitalised and non-hospitalised populations: a narrative synthesis review

  • By

  • Nutan Maurya

  • Agnes Le

  • Gregory Melbourne

  • Josephine Sau Fan Chow

  • May 7, 2026

  • 0 min

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Clinical Report: Long-term Cardiovascular Effects of COVID-19

Overview

This narrative review summarizes the long-term cardiovascular effects of COVID-19 in both hospitalized and non-hospitalized patients. It highlights that while hospitalized patients face a higher risk of severe cardiovascular complications, non-hospitalized individuals may also experience significant cardiac issues.

Background

COVID-19 has been recognized not only as a respiratory illness but also as a condition that can lead to various long-term cardiovascular complications. Understanding the cardiovascular implications of COVID-19 is crucial, especially given the high prevalence of cardiovascular disease globally. The intersection of COVID-19 and cardiovascular health poses significant challenges for patient management and public health.

Data Highlights

Seventy-one studies were included in the review, with follow-up periods ranging from less than 1 month to over 24 months. Hospitalized patients reported more frequent cardiovascular symptoms, while echocardiographic abnormalities were noted across all groups.

Key Findings

  • Hospitalized patients are at a higher risk for long-term cardiovascular complications, including myocardial injury and heart failure.
  • Common cardiovascular symptoms in long COVID include palpitations, chest pain, fatigue, and arrhythmias.
  • Non-hospitalized individuals may experience subclinical cardiac changes despite mild or asymptomatic COVID-19.
  • Vaccination appears to have a protective effect against long-term cardiovascular complications.
  • Standardized, prospective studies are needed to clarify long-term cardiovascular risks and guide follow-up care.

Clinical Implications

Healthcare professionals should be vigilant in monitoring both hospitalized and non-hospitalized COVID-19 patients for cardiovascular symptoms. The findings underscore the importance of vaccination and structured follow-up care to mitigate long-term cardiovascular risks.

Conclusion

The long-term cardiovascular effects of COVID-19 are significant and warrant attention in both clinical practice and future research. Understanding these implications is essential for improving patient outcomes.

Related Resources & Content

  1. Tsampasian V., European Journal of Preventive Cardiology, 2023 -- Cardiovascular disease as part of Long COVID: a systematic review
  2. Conexiant, 2023 -- Long COVID May Raise Cardiovascular Risk
  3. European Journal of Preventive Cardiology, 2023 -- Behind the shadows: bringing the cardiovascular secrets of long COVID into light
  4. Clinical Research in Cardiology, 2020 -- Immediate Cardiac Outcomes in COVID-19 Survivors: A Systematic Review Post-Hospitalization
  5. European Journal of Preventive Cardiology, 2025 -- Cardiovascular disease prevention and management in COVID-19: a clinical consensus statement
  6. ScienceDirect, 2026 -- Long COVID and risk of incident cardiovascular disease: a prospective cohort study
  7. Cardiovascular disease prevention and management in COVID-19: a clinical consensus statement of the European Association of Preventive Cardiology, the European Association of Cardiovascular Imaging, the Association of Cardiovascular Nursing & Allied Professions, the European Association of Percutaneous Cardiovascular Interventions, and the Heart Failure Association of the ESC | European Journal of Preventive Cardiology | Oxford Academic
  8. Long COVID and risk of incident cardiovascular disease: a prospective cohort study using the Multimorbidity Integrated Registry Across Care Levels in Stockholm (MIRACLE-S) cohort - ScienceDirect

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